Which Amendment addresses the issue of self-incrimination?

The Fifth Amendment is significant because it specifically addresses the issue of self-incrimination through its protection against being compelled to testify against oneself in a criminal case. This provision is crucial to ensuring that individuals have the right to remain silent and not provide evidence that could lead to their own conviction. This safeguard plays a vital role in the criminal justice system, as it helps maintain the presumption of innocence until proven guilty. The principle is intended to avoid forcing individuals into a position where they could inadvertently contribute to their own prosecution, underscoring the importance of fair legal representation and the protection of individual rights during legal proceedings.